The Compressed Gas Association (CGA) has released the 2025 editions of CGA P-2.5 and CGA P-2.6, two cornerstone publications that define best practices for the transfilling of oxygen used for respiration. These updated standards reflect the latest safety insights, regulatory changes, and industry advancements—making them essential resources for manufacturers, distributors, and health care facilities involved in oxygen handling.
What’s New in the 2025 Editions?
Both documents have been revised to provide expanded guidance on hazards and safety precautions, as well as updated references to U.S. and Canadian regulations, including those from the FDA, DOT, OSHA, Health Canada, and Transport Canada. Technical changes are clearly marked, making it easy for users to identify what’s been updated from previous editions.
CGA P-2.5—2025: Standard for Transfilling of High-Pressure Gaseous Oxygen Used for Respiration
This standard focuses on the transfilling of high-pressure gaseous oxygen cylinders for respiratory use. It outlines the risks associated with oxygen’s oxidizing properties, contamination, and combustion, and emphasizes the need for trained personnel and oxygen-compatible equipment.
Key updates and coverage include:
- Detailed safety protocols for transfilling operations
- Equipment specifications for valves, regulators, hoses, and pressure relief devices
- Inspection and labeling requirements for cylinders
- Normative appendices with temperature-pressure filling charts in both U.S. customary and SI units
- Expanded regulatory guidance for compliance with FDA, DOT, OSHA, and Health Canada
Whether you’re a gas supplier or a medical facility, CGA P-2.5 provides the framework to ensure safe, compliant, and efficient gaseous oxygen transfilling.
CGA P-2.6—2025: Standard for Transfilling of Liquid Oxygen Used for Respiration
CGA P-2.6 addresses the transfilling of cryogenic liquid oxygen—a process that presents unique challenges due to the extreme cold and high expansion ratio of liquid oxygen. This standard is designed to help organizations mitigate risks such as frostbite, combustion, and pressure buildup while maintaining regulatory compliance.
Highlights of the 2025 edition include:
- Comprehensive guidance on cryogenic container design, labeling, and pressure control
- Safety protocols for vehicle-mounted units and bulk storage tanks
- Requirements for transfer devices, measurement tools, and personal protective equipment (PPE)
- Best practices for container maintenance and storage
- Updated regulatory references for both U.S. and Canadian jurisdictions
CGA P-2.6 is an indispensable resource for anyone involved in the handling and transfilling of liquid oxygen for medical use.
Why These Standards Matter
Oxygen is a life-sustaining gas—but its handling demands precision, care, and compliance. The 2025 editions of CGA P-2.5 and P-2.6 empower organizations to meet these demands with confidence. Whether you’re updating your SOPs, training staff, or preparing for regulatory audits, these publications provide the clarity and authority you need.
Ready to stay ahead of the curve?
Visit www.cganet.com to purchase your copies and explore the full library of CGA safety standards.