Oxygen is a versatile gas with many uses. The principal benefits of oxygen come from its life-sustaining and combustion-supporting properties. However, the ability to support and enhance combustion also creates the accompanying hazards.

In June 2026, CGA published a newly revised harmonized third edition of CGA P-45, Fire Hazards of Oxygen and Oxygen-enriched Atmospheres. The goal of CGA P-45 is to provide guidance for personnel working with oxygen or working in a location that has the potential to become an oxygen-enriched atmosphere.

The main outline of CGA P-45 is shown below:

• General properties of oxygen
• Fire hazards with oxygen
• Prevention of fires in oxygen systems
• Methods of oxygen detection
• Protection of personnel.

Appendix A is a summary of the information in CGA P-45 that is suitable as a free-standing pamphlet. The pamphlet can be given to personnel who are involved in operations with oxygen or oxygen-enriched atmospheres.

Appendix B lists examples of incidents that illustrate the hazards of oxygen and oxygen-enriched atmospheres.

The 2026 edition of CGA P-45 (upgraded from the 2018 edition) has been revised editorially for improved clarity of presentation.