CGA’s February 2022 Safety Publications (New Releases & Revisions)

March 25, 2022

During February 2022, the Compressed Gas Association (CGA) issued the following new and revised safety standards, guidelines, and safety alerts:

CGA C-17, Methods to Avoid and Detect Internal Corrosion of Gas Cylinders and Tubes

Released: February 1, 2022 (3rd Edition)
Special Attribute: Harmonized publication

This publication provides guidance to help prevent and detect internal corrosion of compressed gas cylinders and tubes. It applies to gas cylinders, bundles of cylinders, and tubes including installations at customer sites.

The main emphasis of CGA C-17 focuses on steel cylinders containing oxygen/oxygen mixtures including compressed air and carbon dioxide/carbon dioxide mixtures in the presence of moisture. Certain aspects of this publication can also apply to other gases that can react in the presence of moisture, such as hydrogen chloride.

CGA G-6.5, Standard for Small Stationary Insulated Carbon Dioxide Supply Systems

Released: February 23, 2022 (5th Edition)
Special Attribute: Referenced by NFPA (National Fire Protection Association)

This publication addresses the hazards specifically associated with small stationary insulated carbon dioxide supply systems. The purpose of safety publication CGA G-6.5 is to provide a standard for small stationary insulated carbon dioxide systems with the capacity of each container being 1000 lb (454 kg) or less. It is intended to assist designers, engineers, distributors, restaurant personnel, inspectors, other users, and all interested parties.

While this standard is to be used as a guide for user installations, final approval of the design, equipment, appurtenances, and installation rests with the authority having jurisdiction (AHJ) in this area.

CGA M-16, Standard for Food, Drug, and Medical Device Gas and Gas Equipment Manufacturers on Electronic Records and Signatures

Released: February 23, 2022 (2nd Edition)

This safety publication is based on the U.S. Food and Drug Administration’s August 2003 Guidance for Industry Part 11, Electronic Records; Electronic Signatures—Scope and Application. CGA M-16 satisfies the criteria of Title 21 of the U.S. Code of Federal Regulations (21 CFR) Part 11, § 11.1 (a) “The regulations in this part set forth the criteria under which the agency considers electronic records, electronic signatures, and handwritten signatures executed to electronic records to be trustworthy, reliable, and generally equivalent to paper records and handwritten signatures executed on paper.”

CGA M-16 also harmonizes with PIC/S Guide for good manufacturing practice for medicinal products, Annex 11 “Computerised Systems” (as adopted in Canada).

In addition to the guidance in this publication, see CGA M-27, Guideline for Complying with Data Integrity Regulatory Expectations, for more information on compliance with data integrity requirements for medical gases.

CGA M-17, Standard for Automatic Trailer Fill Compliance to 21 CFR Part 11 and PIC/S Annex 11 Requirements

Released: February 23, 2022 (2nd Edition)

CGA M-17 applies to ATF systems and records, including trailers, microbulk vessels, railcars, and ISO containers at bulk medical gas and bulk food gas manufacturing facilities.

In addition to the guidance in this publication, see CGA M-27, Guideline for Complying with Data Integrity Regulatory Expectations, for more information on compliance with data integrity requirements for ATF systems.

CGA P-9, The Inert Gases: Argon, Nitrogen, and Helium

Released: February 1, 2022 (6th Edition)

The purpose of safety publication CGA P-9 is to present information regarding the characteristics and handling of the three major inert gases – argon, nitrogen, and helium. Requests for specialized technical information should be directed to any one of the manufacturers of these gases.

This publication is intended primarily for users of the inert gases. Some of the requirements do not apply to the manufacturers or distributors of these gases.

CGA P-29, Guideline for the Application of OSHA PSM and EPA RMP to the Compressed Gas Industry

Released: February 1, 2022 (5th Edition)

CGA P-29 defines the criteria that may be applied to industrial gas facilities to evaluate the scope and extent of application of the U.S. Occupational Safety and Health Administration (OSHA) Process Safety Management (PSM) standard and the U.S. Environmental Protection Agency (EPA) Risk Management Program (RMP).

This guidance document also:

• explains how the PSM standard and the RMP rule apply to processes commonly found in the gas industry
• defines criteria that can be used to determine if a process is covered by the PSM standard or the RMP rule
• establishes a basis for determining reasonable boundaries of covered processes
• explains the major differences between the PSM standard and the RMP rule
• explains the exemptions allowed under each regulation

CGA P-34, Safe Handling of Ozone-Containing Mixtures Including the Installation and Operation of Ozone-Generating Equipment

Released: February 1, 2022 (3rd Edition)

This safety publication presents general information regarding the characteristics of ozone, the means by which it can be handled safely, and the safe installation and operation of ozone-generating equipment. Requests for specialized, technical information regarding specific types of ozone-generating equipment should be directed to the manufacturers of equipment used to produce ozone gas.

CGA P-34 is intended primarily for users of ozone and manufacturers of equipment used to produce ozone. It is limited to dry (less than 100 ppm moisture) oxygen-ozone, air-ozone mixtures at pressures up to 2 atm (gauge), and up to 16 weight percent ozone.

CGA S-1.1, Pressure Relief Device Standards-Part 1-Cylinders for Compressed Gases

Released: February 23, 2022 (16th Edition)
Special Attribute: Referenced by NFPA (National Fire Protection Association) and ICC (International Code Council)

This standard applies to the selection of PRDs for a single component compressed gas in cylinders. For selection of PRDs for compressed gas mixtures in cylinders, see CGA S-7, Standard Method for Selecting Pressure Relief Devices for Compressed Gas Mixtures in Cylinders.

CGA S-1.1 does not cover PRD requirements for CTC/DOT-4L and TC-4LM insulated cylinders containing cryogenic liquids, see CGA S-1.2, Pressure Relief Device Standards-Part 2-Portable Containers for Compressed Gases. This standard does not cover PRD requirements for multi-unit tank car tanks (DOT106A/TC106A and DOT110A-W/TC110A), see Title 49 of the U.S. Code of Federal Regulations (49 CFR) 179.300-15 and CGSB 43.147, Construction, Modification, Qualification, Maintenance, and Selection and Use of Means of Containment for the Handling, Offering for Transport, or Transporting of Dangerous Goods by Rail, as appropriate.

This publication includes tables that provide information pertaining to PRDs.

For pressure relief device standards for bulk transport containers and stationary storage containers, see CGA S-1.2 and CGA S-1.3, Pressure Relief Device Standards-Part 3-Stationary Storage Containers for Compressed Gases.

CGA SA-35, Safety Alert, Cleaning of Cylinders Returned from Health Care Facilities During a Pandemic

Released: February 23, 2022 (2nd Edition)

As health care providers around the world work to assist patients affected by the respiratory illness Coronavirus Disease 2019 (COVID-19), medical gas containers might become externally contaminated due to their use in health care facilities.

It is important that these containers are cleaned in a manner that removes contaminants, does not cause damage to the container, valve, or gas product, and does not lead to a hazardous situation during the refilling and use of the container’s contents.